The volume collects the contributions presented at the international conference Hominis 2023 (Havana, Cuba, 24-28 April 2023), in its ninth edition, entitled “Psicologia viva al servicio de sus pueblos”. In particular, the contributions of some theorists and scholars of Vygoskian thought presented at the Symposium “The Zone of Proximal Development (ZDP) in the School Education and Clinical Practice” are collected here. Therefore, the collection edited here resulted from an enriching and constructive international meeting that saw the profitable synergy between scholars of different countries involved in research, expanding a multicultural approach to psycho-pedagogical development and learning.The edition of the present volume represents to the editor the opportunity to synthesise the state of historical-cultural psychology, mainly when applied in clinical and didactical fields. Thanks to Sapienza’s funding for international agreements, the publication of these proceedings allows for a broad, in-depth analysis, and prospective analysis of the historical-cultural approach proposed by L.S. Vygotskij, a thinker to be appreciated not simply as a semiologist but as a fighter for freedom and overall inclusion in the frame of values of social justice and equality. It is an ambitious attempt, a message to all scholars, colleagues, and students engaged in education and psycho-social interventions.